611 research outputs found

    On the formation of sand ramps: A case study from the Mojave Desert

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    Sand ramps are dune-scale sedimentary accumulations found at mountain fronts and consist of a combination of aeolian sands and the deposits of other geomorphological processes associated with hillslope and fluvial activity. Their complexity and their construction by wind, water and mass movement means that sand ramps potentially hold a very rich store of palaeoenvironmental information. However, before this potential can be realised a full understanding of their formation is necessary. This paper aims to provide a better understanding of the principal factors influencing the development of sand ramps. It reviews the stratigraphic, chronometric and sedimentological evidence relating to the past development of sand ramps, focussing particularly on Soldier Mountain sand ramp in the Mojave Desert, as well as using observations of the modern movement of slope material to elucidate the formation of stone horizons within sand ramps. Findings show that sand ramps cannot easily be interpreted in terms of a simple model of fluctuating palaeoenvironmental phases from aeolian dominated to soil/fluvial dominated episodes. They accumulate quickly (perhaps in < 5 ka), probably in a single phase before becoming relict. Based on the evidence from Soldier Mountain, they appear strongly controlled by a ‘window of opportunity’ when sediment supply is plentiful and cease to develop when this sediment supply diminishes and/or the accommodation space is filled up. Contemporary observations of stone movement both on rock and sandy sloping surfaces in the Mojave region indicate movement rates in the order of 0.6 and 11 mm yr− 1, which is insufficiently fast to explain how stone horizons could have been moved across and been incorporated into sand ramps on multiple occasions. Stone horizons found within the aeolian sediments lack evidence for soil development and are interpreted as very short-term events in which small streams moved and splayed discontinuous stone horizons across the sand ramp surface before aeolian deposition resumed. Surface stone horizons may form by creep from mountain slope sources across sand ramps but require enhanced speed compared to measured rates of runoff creep. We propose the mechanism of fluvio-aeolian creep. Our study suggests that current models of alternating aeolian and colluvial deposition within sand ramps, their palaeoenvironmental significance and indeed how sand ramps are distinguished from other dune forms require amendment

    Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases.

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    Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target. It is hypothesized that cellular enlargement requires regional expansion of the cell wall through coordinated insertion and hydrolysis of peptidoglycan. Here, a group of (apparent glucosaminidase) peptidoglycan hydrolases are identified that are together required for cell enlargement and correct cellular morphology of Staphylococcus aureus, demonstrating the overall importance of this enzyme activity. These are Atl, SagA, ScaH, and SagB. The major advance here is the explanation of the observed morphological defects in terms of the mechanical and biochemical properties of peptidoglycan. It was shown that cells lacking groups of these hydrolases have increased surface stiffness and, in the absence of SagB, substantially increased glycan chain length. This indicates that, beyond their established roles (for example in cell separation), some hydrolases enable cellular enlargement by making peptidoglycan easier to stretch, providing the first direct evidence demonstrating that cellular enlargement occurs via modulation of the mechanical properties of peptidoglycan. IMPORTANCE: Understanding bacterial growth and division is a fundamental problem, and knowledge in this area underlies the treatment of many infectious diseases. Almost all bacteria are surrounded by a macromolecule of peptidoglycan that encloses the cell and maintains shape, and bacterial cells must increase the size of this molecule in order to enlarge themselves. This requires not only the insertion of new peptidoglycan monomers, a process targeted by antibiotics, including penicillin, but also breakage of existing bonds, a potentially hazardous activity for the cell. Using Staphylococcus aureus, we have identified a set of enzymes that are critical for cellular enlargement. We show that these enzymes are required for normal growth and define the mechanism through which cellular enlargement is accomplished, i.e., by breaking bonds in the peptidoglycan, which reduces the stiffness of the cell wall, enabling it to stretch and expand, a process that is likely to be fundamental to many bacteria

    Exploratory Measurements of the (3-He,n) Reaction at Medium Energies

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    This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit

    The eta' meson from lattice QCD

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    We study the flavour singlet pseudoscalar mesons from first principles using lattice QCD. With N_f=2 flavours of light quark, this is the so-called eta_2 meson and we discuss the phenomenological status of this. Using maximally twisted-mass lattice QCD, we extract the mass of the eta_2 meson at two values of the lattice spacing for lighter quarks than previously discussed in the literature. We are able to estimate the mass value in the limit of light quarks with their physical masses.Comment: 16 pages: version accepted for publicatio

    Changes in white matter microstructure and MRI-derived cerebral blood flow after one-week of exercise training

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    Exercise is beneficial for brain health, inducing neuroplasticity and vascular plasticity in the hippocampus, which is possibly mediated by brain-derived neurotrophic factor (BDNF) levels. Here we investigated the short-term effects of exercise, to determine if a 1-week intervention is sufficient to induce brain changes. Fifteen healthy young males completed five supervised exercise training sessions over seven days. This was preceded and followed by a multi-modal magnetic resonance imaging (MRI) scan (diffusion-weighted MRI, perfusion-weighted MRI, dual-calibrated functional MRI) acquired 1 week apart, and blood sampling for BDNF. A diffusion tractography analysis showed, after exercise, a significant reduction relative to baseline in restricted fraction—an axon-specific metric—in the corpus callosum, uncinate fasciculus, and parahippocampal cingulum. A voxel-based approach found an increase in fractional anisotropy and reduction in radial diffusivity symmetrically, in voxels predominantly localised in the corpus callosum. A selective increase in hippocampal blood flow was found following exercise, with no change in vascular reactivity. BDNF levels were not altered. Thus, we demonstrate that 1 week of exercise is sufficient to induce microstructural and vascular brain changes on a group level, independent of BDNF, providing new insight into the temporal dynamics of plasticity, necessary to exploit the therapeutic potential of exercise

    Minimum Wages and Poverty with Income-Sharing

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    Textbook analysis tells us that in a competitive labor market, the introduction of a minimum wage in terms of poverty rather than in terms of unemployment. This paper makes three contributions to the basic theory of the minimum wage. First, we analyze the effects of a higher minimum wage in terms of poverty rather than in terms of unemployment. Second, we extend the standard textbook model to allow for income-sharing between employed and unemployed persons in society. Third, we extend the basic model to deal with income sharing within families. We find that there are situations in which a higher minimum wage raises poverty, others where it reduces poverty, and yet others in which poverty is unchanged. We characterize precisely how the poverty effect depends on four parameters: the degree of poverty aversion, the elasticity of labor demand, the ratio of the minimum wage to the poverty line, and the extent of income-sharing. Thus, shifting the perspective from unemployment to poverty leads to a considerable enrichment of the theory of the minimum wage

    Cardiometabolic Risk Assessments by Body Mass Index z -Score or Waist-to-Height Ratio in a Multiethnic Sample of Sixth-Graders

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    Convention defines pediatric adiposity by the body mass index z-score (BMIz) referenced to normative growth charts. Waist-to-height ratio (WHtR) does not depend on sex-and-age references. In the HEALTHY Study enrollment sample, we compared BMIz with WHtR for ability to identify adverse cardiometabolic risk. Among 5,482 sixth-grade students from 42 middle schools, we estimated explanatory variations (R2) and standardized beta coefficients of BMIz or WHtR for cardiometabolic risk factors: insulin resistance (HOMA-IR), lipids, blood pressures, and glucose. For each risk outcome variable, we prepared adjusted regression models for four subpopulations stratified by sex and high versus lower fatness. For HOMA-IR, R2 attributed to BMIz or WHtR was 19%-28% among high-fatness and 8%-13% among lower-fatness students. R2 for lipid variables was 4%-9% among high-fatness and 2%-7% among lower-fatness students. In the lower-fatness subpopulations, the standardized coefficients for total cholesterol/HDL cholesterol and triglycerides tended to be weaker for BMIz (0.13-0.20) than for WHtR (0.17-0.28). Among high-fatness students, BMIz and WHtR correlated with blood pressures for Hispanics and whites, but not black boys (systolic) or girls (systolic and diastolic). In 11-12 year olds, assessments by WHtR can provide cardiometabolic risk estimates similar to conventional BMIz without requiring reference to a normative growth chart

    A Study of the Roper Resonance as a Hybrid State from J/ψJ/\psi Decays

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    The structure of the Roper resonance as a hybrid baryon is investigated through studying the transitional amplitudes in J/psi-> p\barN*, N*\barN* decays. We begin with perturbative QCD to describe the dynamical process for the J/psi-> 3\bar q+3q decay to the lowest order of \alpha_s, and by extending the modified quark creation model to the J/psi energy region to describe the J/psi-> 3\bar q+3q +g process. The non-perturbative effects are incorporated by a simple quark model of baryons to evaluate the angular distribution parameters and decay widths for the processes J/psi-> pbar N*,N*bar N*. From fitting the decay width of J/psi->gamma p pbar to the experimental data, we extract the quark-pair creation strength g_I=15.40 GeV. Our numerical results for J/psi->pbar N*,N* bar N* decays show that the branching ratios for these decays are quite different if the Roper resonance is assumed to be a common 3q3q state or a pure hybrid state. For testing its mixing properties, we present a scheme to construct the Roper wave function by mixing |qqqg> state with a normal |qqq,2s> state. Under this picture, the ratios of the decay widths to that of the J/psi->p pbar decay are re-evaluated versus the mixing parameter. A test of the hybrid nature of the Roper resonance in J/psi decays is discussed.Comment: 18 pages,3 figures, To appear in Nuclear Physics

    Anthropogenic Space Weather

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    Anthropogenic effects on the space environment started in the late 19th century and reached their peak in the 1960s when high-altitude nuclear explosions were carried out by the USA and the Soviet Union. These explosions created artificial radiation belts near Earth that resulted in major damages to several satellites. Another, unexpected impact of the high-altitude nuclear tests was the electromagnetic pulse (EMP) that can have devastating effects over a large geographic area (as large as the continental United States). Other anthropogenic impacts on the space environment include chemical release ex- periments, high-frequency wave heating of the ionosphere and the interaction of VLF waves with the radiation belts. This paper reviews the fundamental physical process behind these phenomena and discusses the observations of their impacts.Comment: 71 pages, 35 figure

    Can forest management based on natural disturbances maintain ecological resilience?

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    Given the increasingly global stresses on forests, many ecologists argue that managers must maintain ecological resilience: the capacity of ecosystems to absorb disturbances without undergoing fundamental change. In this review we ask: Can the emerging paradigm of natural-disturbance-based management (NDBM) maintain ecological resilience in managed forests? Applying resilience theory requires careful articulation of the ecosystem state under consideration, the disturbances and stresses that affect the persistence of possible alternative states, and the spatial and temporal scales of management relevance. Implementing NDBM while maintaining resilience means recognizing that (i) biodiversity is important for long-term ecosystem persistence, (ii) natural disturbances play a critical role as a generator of structural and compositional heterogeneity at multiple scales, and (iii) traditional management tends to produce forests more homogeneous than those disturbed naturally and increases the likelihood of unexpected catastrophic change by constraining variation of key environmental processes. NDBM may maintain resilience if silvicultural strategies retain the structures and processes that perpetuate desired states while reducing those that enhance resilience of undesirable states. Such strategies require an understanding of harvesting impacts on slow ecosystem processes, such as seed-bank or nutrient dynamics, which in the long term can lead to ecological surprises by altering the forest's capacity to reorganize after disturbance
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